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PubMed COVID-19 Clinical Care

3891 - 3900 of 4931 results found

Evaluation of off-label rapamycin use to promote healthspan in 333 adults

Date
Tuesday, May 16, 2023 - 4:00 AM
Description
Rapamycin (sirolimus) is an FDA-approved drug with immune-modulating and growth-inhibitory properties. Preclinical studies have shown that rapamycin extends lifespan and healthspan metrics in yeast, invertebrates, and rodents. Several physicians are

Endomembrane remodeling in SARS-CoV-2 infection

Date
Tuesday, May 16, 2023 - 4:00 AM
Description
During severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the viral proteins intimately interact with host factors to remodel the endomembrane system at various steps of the viral lifecycle. The entry of SARS-CoV-2 can be